Approaches: Molecular Genetics PRISM Electrophysiology Neuroanatomy in vivo Imaging Behavioral Analyses Bridging Mice and Men	Our laboratory uses a number of approaches to study learning and memory at multiple levels of analyses. Essentially, we use the best possible techniques we can to address the problems we are studying. Our approaches include:
Integrating findings in the neuroscience of memory...
Genes Although many of our studies include mice with defined mutations, we have also taken advantage of a number of other strategies to manipulate molecular function in the brain, including pharmacology and gene transfer with viral vectors. We are also taking advantage of molecular systems to activate and inactivate cells	Neurons/Systems We use slice electrophysiology to study the cell biology of learning and memory, and neuroanatomic lesions to assess the role of specific brain regions. We are developing new technologies for  time-lapse two-photon confocal imaging in vivo to define cellular neurosystems and dendritic structural changes during memory.	Behavior Most of our studies start with extensive behavioral analyses. For this purpose our laboratory uses a number of tests that allow us to evaluate a wide range of rodent behaviors. We have also initiated cognitive neuroscience studies with patients using techniques such as brain imaging
Is there a perfect technique to address a problem? see our studies on S2 >>
The Molecular and Cellular Cognition Society There is a society for laboratories (like ours) interested in a molecular to behavioral, multiple-level analysis of cognition. For information concerning the Molecular and Cellular Cognition Society click here
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