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memory and its disorders

Our laboratory at UCLA is studying learning, memory and its disorders.

Our field of study is Molecular and Cellular Cognition. The goal of this field is to derive explanations of cognitive processes that integrate molecular, cellular, circuit and behavioral mechanisms and to find treatments for cognitive disorders. We are part of the UCLA Integrative Center for Learning and Memory.

  • We are searching for the molecular, cellular and circuit processes that underlie the encoding, allocation, storage and linking of information in the brain.
  • Insights into mechanisms of memory are being used to unravel the causes and develop treatments for cognitive deficits associated with aging, intellectual disabilities, and autism. Recently, our studies in mice suggested that it is possible to reverse neurodevelopmental disorders, such as intellectual disabilities associated with mutations in NF1, TSC and DISC1 in adults.
  • Additionally, we hope our studies of the mechanisms underlying extraordinary cognitive function may lead to general treatments for cognitive disorders and to faster recovery after brain injury.
  • Our laboratory is developing bioinformatic strategies to address the growing complexity of the literature. For example, we recently developed a free web application to keep track of causal information in research papers (researchmaps.org). The resulting research maps and graphing tools are invaluable for integrating and planning experiments.